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Injected every 12 months. The only real continuing action is usually to book subsequent stick to-up injections each individual twelve weeks, and to observe Unwanted effects to ensure that they don't need professional medical focus.[citation desired]
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MPA is actually a potent agonist from the progesterone receptor with comparable affinity and efficacy relative to progesterone.[131] Whilst each MPA and its deacetylated analogue medroxyprogesterone bind to and agonize the PR, MPA has approximately a hundred-fold larger binding affinity and transactivation potency compared.[131] As a result, as opposed to MPA, medroxyprogesterone just isn't employed clinically, nevertheless it has found some use in veterinary medicine.